Jacqueline Otto

Jacqueline Otto
Graduate Student
119 McAlester Hall
Lab Area: 
Research Interests: 

My program of research aims to characterize the molecular genetic and epigenetic influences on liability for alcohol and tobacco use and dependence. Specific interests include the application of statistical genetic and bioinformatic approaches, and extending this work to correlates of psychiatric comorbidity and intermediate phenotypes more broadly.

Selected Publications: 

Otto, J. M., Gizer, I. R., Deak, J. D., Fleming, K. A., & Bartholow, B. D. (2017). A cis-eQTL in OPRM1 is associated with subjective response to alcohol and alcohol use. Alcoholism: Clinical and Experimental Research, 41, 929-938. doi: 10.1111/acer.13369

Otto, J. M., Gizer, I. R., Ellingson, J. M., & Wilhelmsen, K. C. (2017). Genetic variation in the exome: Associations with alcohol and tobacco co-use. Psychology of Addictive Behaviors, 31, 354-366. doi: 10.1037/adb0000270

Richmond-Rakerd, L. S., Gizer, I. R., Otto, J. M., Ellingson, J. M., Bizon, C., Peng, Q., Norden-Krichmar, T., Ehlers, C. L., & Wilhelmsen, K. C. (2017). A novel tobacco use phenotype suggests the 15q25 and 19q13 loci may be differentially associated with cigarettes per day and tobacco-related problems. Nicotine and Tobacco Research, 19, 426-434. doi: 10.1093/ntr/ntw260

Otto, J. M., Gizer, I. R., Ellingson, J. M., Bizon, C., Wilhelmsen, K. C., Ehlers, C. L. (2016). Polygenic risk scores for cigarettes smoked per day do not generalize to a Native American population. Drug and Alcohol Dependence, 167, 95-102. doi: 10.1016/j.drugalcdep.2016.07.029

George, W. H., Davis, K. C., Masters, T. N., Jacques-Tiura, A. J., Heiman, J. R., Norris, J., Gilmore, A. K., Nguyen, H. V., Kajumulo, K. F., Otto, J. M., & Andrasik, M. P. (2014). Sexual victimization, alcohol intoxication, sexual-emotional responding, and sexual risk in heavy episodic drinking women. Archives of Sexual Behavior, 43, 645-658. doi:10.1007/s10508-013-0143-8

Masters, N. T., George, W. H., Davis, K. C., Norris, J., Heiman, J. R., Jacques-Tiura, A. J., Gilmore, A. K., Nguyen, H. V., Kajumulo, K. F., Otto, J. M., & Stappenbeck, C. A. (2014). Women’s unprotected sex intentions: Roles of sexual victimization, intoxication, and partner perception. Journal of Sex Research, 51, 586-598. doi:10.1080/00224499.2012.763086

Otto, J. M., Hendershot, C. S., Collins, S. E., Tiebing, L., & Wall, T. M. (2013). Association of the ALDH1A1*2 polymorphism with alcohol phenotypes in young adults with or without ALDH2*2. Alcoholism – Clinical and Experimental Research, 37, 164-169. doi:10.1111/j.1530-0277.2012.01835.x

Andrasik, M. P., Otto, J. M., Nguyen, H. V., Burris, L. D., Gilmore, A. K., George, W. H., Kajumulo, K. F., & Masters, T. (2013). The potential of alcohol “heat-of-the-moment” scenarios in HIV prevention: A qualitative study exploring intervention implications. Archives of Sexual Behavior, 42, 1487-1499. doi:10.1007/s10508-013-0125-x

Nguyen, H. V., Koo, K., Davis, K. C., Otto, J. M., Hendershot, C. S., Schacht, R. L., George, W. H., Heiman, J. R., Norris, J., & Stoner, S. A. (2012). Risky sex: Interactions among ethnicity, sexual sensation seeking, sexual inhibition, and sexual excitation. Archives of Sexual Behavior, 41, 1231-1239. doi:10.1007/s10508-012-9904-z

Lindgren, K. P., Hendershot, C. S., Neighbors, C., Blayney, J. A., & Otto, J. M. (2011). Implicit alcohol motives predict unique variance in drinking in Asian-American College Students. Motivation and Emotion, 35, 435–443. doi:10.1007/s11031-011-9223-z

Hendershot, C. S., Witkiewitz, K., George, W. H., Wall, T. M., Otto, J. M., Liang, T., & Larimer, M. E. (2011). Extending a cognitive model of ALDH2 and drinking behavior. Alcoholism – Clinical and Experimental Research, 35, 91-98. doi:10.1111/j.1530-0277.2010.01325.x

Hendershot, C. S., Otto, J. M., Collins, S. E., Liang, T., & Wall, T. M. (2010). Evaluation of a brief web-based genetic feedback intervention for reducing alcohol-related risks associated with ALDH2. Annals of Behavioral Medicine, 40, 77-88. doi:10.1007/s12160-010-9207-3

Gilmore, A. K., Schacht, R. L., George, W. H., Otto, J. M., Davis, K. C., Heiman, J. R., Norris, J., & Kajumulo, K. F. (2010). Assessing women’s sexual arousal in the context of sexual assault history and acute alcohol intoxication. Journal of Sexual Medicine, 7, 2112-2119. doi:10.1111/j.1743-6109.2010.01786.x

Collins, S. E., Carey, K. B., & Otto, J. M. (2009). A new decisional balance measure of motivation to change among at-risk college drinkers. Psychology of Addictive Behaviors, 23, 464-471. doi:10.1037/a0015841

Collins, S. E., Chawla, N., Hsu, S. H., Grow, J., Otto, J. M., & Marlatt, G. A. (2009). Language-based measures of mindfulness: Initial validity and clinical utility. Psychology of Addictive Behaviors, 23, 743-749. doi:10.1037/a0017579

BOOK CHAPTERS

Gizer, I.R., Otto, J.M., & Ellingson, J.M. (2015). Molecular Genetic Approaches to Studying the Externalizing Spectrum. In T. Beauchaine & S. Hinshaw (Eds.), Oxford Handbook on Externalizing Spectrum Disorders (pp. 125-148). New York, NY: Oxford University Press. doi: 10.1093/oxfordhb/9780199324675.013.24

Gizer, I.R., Otto, J.M., & Ellingson, J.M. (2015). Molecular Genetics of the Externalizing Spectrum. In T. Beauchaine & S. Hinshaw (Eds.), Oxford Handbook on Externalizing Spectrum Disorders (pp. 149-169). New York, NY: Oxford University Press. doi: 10.1093/oxfordhb/9780199324675.013.29